Lois Mulligan, PhD
Department of Pathology and Molecular Medicine, and Division of Cancer Biology and Genetics, Cancer Research Institute at Queen’s University, Kingston, Canada
Dr. Lois Mulligan is a molecular and cellular biologist with research interests in exploring the regulation of key signalling pathways involved in both tumorigenesis and normal development. Her research focuses on the application of genetic, cell and molecular approaches to characterization of the structure, localization and functions of a cell surface protein of the receptor tyrosine kinase family, called RET. Her lab is exploring the mechanisms regulating RET’s functions in neuroendocrine development, and in initiation, progression and spread of multiple cancer types. This work is identifying novel regulatory mechanisms associated with isoform specific trafficking and localization of RET proteins and how these impact on cellular functions in vitro and in vivo.