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MicroRNA profiling in plasma of HIV-1 infected patients: potential markers of infection and immune status

  
@article{JPHE4029,
	author = {Yuhua Qi and Haiyang Hu and Hongxiong Guo and Peng Xu and Zhiyang Shi and Xiping Huan and Zheng Zhu and Minghao Zhou and Lunbiao Cui},
	title = {MicroRNA profiling in plasma of HIV-1 infected patients: potential markers of infection and immune status},
	journal = {Journal of Public Health and Emergency},
	volume = {1},
	number = {7},
	year = {2017},
	keywords = {},
	abstract = {Background: Circulating miRNAs are recently used as promising biomarkers for infectious diseases. The aim of this study was to identify plasma miRNAs for infection detection and monitoring the immune status of HIV infection.
Methods: A cohort of 128 plasma samples from HIV-1 infected subjects and 37 samples from healthy donors were analyzed by TaqMan Low-Density Array (TLDA) method to find the differentially expressed miRNAs, in the light of HIV-1infected patients with low (350 cell/μL) CD4+ T cell count.
Results: Seven miRNAs (miR-29a, miR-223, miR-27a, miR-19b, miR-151-3p, miR-28-5p, miR-766 and miR-30a-3p) were significantly associated with CD4+ T cell count (P},
	url = {http://jphe.amegroups.com/article/view/4029}
}