TY - JOUR AU - Shrivastava, Gaurav AU - Benito Gutierrez-Castañeda, Benito Gutierrez-Castañeda AU - Julio García-Cordero, Julio García-Cordero AU - León-Juárez, Moises AU - Cedillo-Barrón, Leticia PY - 2017 TI - IRGB10 supplies bacterial ligands to activate AIM2 and NLRP3 inflammasomes JF - Journal of Public Health and Emergency; Vol 1 (March 2017): Journal of Public Health and Emergency Y2 - 2017 KW - N2 - Recently, Man et al . [2016] published an elegant study in which they showed that immunity-related GTPase family member b10 (IRGB10; an interferon-inducible protein) localizes on the cell membrane of bacteria, damages the membrane, and then releases the hidden ligands from the phagosome to the host-cytoplasm to be sensed by both the absent in melanoma 2 (AIM2) and the noncanonical NLR family pyrin domain-containing (NLRP) inflammasomes (1). UR - https://jphe.amegroups.org/article/view/3808