%0 Journal Article %T IRGB10 supplies bacterial ligands to activate AIM2 and NLRP3 inflammasomes %A Shrivastava, Gaurav %A Benito Gutierrez-Castañeda, Benito Gutierrez-Castañeda %A Julio García-Cordero, Julio García-Cordero %A León-Juárez, Moises %A Cedillo-Barrón, Leticia %J Journal of Public Health and Emergency %D 2017 %B 2017 %9 %! IRGB10 supplies bacterial ligands to activate AIM2 and NLRP3 inflammasomes %K %X Recently, Man et al . [2016] published an elegant study in which they showed that immunity-related GTPase family member b10 (IRGB10; an interferon-inducible protein) localizes on the cell membrane of bacteria, damages the membrane, and then releases the hidden ligands from the phagosome to the host-cytoplasm to be sensed by both the absent in melanoma 2 (AIM2) and the noncanonical NLR family pyrin domain-containing (NLRP) inflammasomes (1). %U https://jphe.amegroups.org/article/view/3808 %V 1 %P %@ 2520-0054